The opening ceremony of the 12th international stroke summit started at 8am on June 18th. The precedent of the ISS, Prof Xinfeng LIU made a welcome speech and introduced the well-known experts and scholars at present. Prof Yongjun WANG, the president of China Stroke Association and Beijing Tiantan Hospital, appreciated the contribution Prof LIU has made for the stroke field. He mentioned that Prof LIU has cultivated and trained many excellent young doctors. Prof Peng XIE, the chairman of neurology department in China Medical Association and Chongqing Medical University, pointed out that the 12-year progresses of the conference also represent the developmental history of cerebrovascular intervention. This platform attaches importance to interventional therapy, which can improve medical education and primary physician training. At last, Prof Raul Nogueira, the co-editor-in-chief of Interventional Neurology, from Emory University in America, and the president of Jinling Hospital, Prof Zhaorong SHI, both gave a speech in the ceremony, expressing anticipations for the summit and welcoming for all the meeting delegates.