《Cerebrovasc Diseases》: China Interventional Stroke Registry: Rationale and Study Design
2013-02-26 13:28:23
 Xinfeng Liu a ,Yunyun Xiong a,Zhiming Zhou d ,Guozhong Niu e ,Wei Wang ,Guodong Xiao c ,Min Lin f
Thomas W. Leung g  Dezhi Liu a  ,Wenhua Liu a ,Xiaobin Fan a ,Qin Yin a ,Wusheng Zhu a ,Minmin Ma a
Renliang Zhang a ,Gelin Xu a 

Keywords: Intervention·   Ischemic stroke·   Stent · Angioplasty·   Registry·  



Background:Angioplasty and stenting have recently become attractive options for cerebral large artery stenosis in China. However, there are limited data on safety and longterm outcomes in Chinese patients having undergone cerebral interventional procedures. To address this need, we set up a common database – the China Interventional Stroke Registry (CISR) – to describe patient characteristics, interventional images, periprocedural complications and long-term clinical outcomes and to determine how adherence to guideline-based treatments in the ‘real world’ works in China. Methods:Six medical centers have participated since 2004. They entered into an Internet-based database data on demographics, clinical history and angiography of patients undergoing angioplasty with/without stenting in extracranial arteries (carotid, vertebral and subclavian arteries) and/or intracranial arteries (middle cerebral artery, vertebral artery and basilar artery) in China. CISR is a research-funded project. Results:As of October 2012, we have already collected detailed clinical information on 1,356 patients (age: 63.6 ± 10.2 years, male: 1,084, 79.9%).
The overall data quality is good. Site data quality control is supported via detailed monthly feedback reports and quarterly data monitoring meetings. Conclusions:The CISR is the first and the largest registry for angioplasty with/without stents in China. The database will provide the characteristics and outcomes of patients and the situation of adherence to guideline-based treatments under ‘real-world’conditions in China.